MUC1 Oncoprotein Stabilizes and Activates Estrogen Receptor α
نویسندگان
چکیده
منابع مشابه
SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation
Estrogen receptor α is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. In our study, we identified the novel E3 ubiquitin ligase SHARPIN function to facilitate ERα signaling. SHARPIN is highly expressed in human breast cancer and correlates with ERα protein level by immunohistochemistry. SHARPIN expression level correlates with poor prognosis in E...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2006
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2005.11.030